Thursday, August 15, 2013

21 Mutational Signatures Of 30 Common Cancers Identified

Milestone Study Probes Cancer Origin by James Gallagher.  BBC News.  August 14, 2013.

Gene Study Uncovers Origins Of Many Common Cancers by Kate Kelland.  Reuters.  August 14, 2013.

(1)  According to the study reported in Nature, disruptive changes to the genetic code have been identified for _____% of the 30 most common cancers.

(2) Two of the most well-known causes of  mutations are _________________.

(3)  These _____________ are hidden within the cancer genome which tell us what is actually causing cancer.

(4)  Signatures related to the body's immune system arise from the collateral damage of responding to _________ infection.

(5)  12 of the 21 identified signatures _________________.

(6)  All cancers examined contained two or more ________________.

(7)  Different cancers have different numbers of _________________.

(8)  Some signatures are found in ____________ when others are found ________________.

(9)  Out of the 30 cancers examined _________ had mutational processes linked to _______>

(10)  A family of enzymes called _________ was linked to more than half of the cancers studied.



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