Showing posts with label DNA. Show all posts
Showing posts with label DNA. Show all posts

Thursday, August 15, 2013

21 Mutational Signatures Of 30 Common Cancers Identified

Milestone Study Probes Cancer Origin by James Gallagher.  BBC News.  August 14, 2013.

Gene Study Uncovers Origins Of Many Common Cancers by Kate Kelland.  Reuters.  August 14, 2013.

(1)  According to the study reported in Nature, disruptive changes to the genetic code have been identified for _____% of the 30 most common cancers.

(2) Two of the most well-known causes of  mutations are _________________.

(3)  These _____________ are hidden within the cancer genome which tell us what is actually causing cancer.

(4)  Signatures related to the body's immune system arise from the collateral damage of responding to _________ infection.

(5)  12 of the 21 identified signatures _________________.

(6)  All cancers examined contained two or more ________________.

(7)  Different cancers have different numbers of _________________.

(8)  Some signatures are found in ____________ when others are found ________________.

(9)  Out of the 30 cancers examined _________ had mutational processes linked to _______>

(10)  A family of enzymes called _________ was linked to more than half of the cancers studied.



Saturday, August 10, 2013

Unforeseen Consequences Of Sharing DNA

Would You Post Your DNA  On Facebook?  by Quentin Fottrell.  August 10, 2013.

(1)  Genealogy companies "operate in a legal gray area."  "They're not quite _________ and they are not quite _________________.

(2)  Even if a genealogy company has a privacy policy stating  that will not sell the DNA, they are still subject to ______________.

(3)  Inviting third parties to use DNA in internal research may not violate _______________.

(4) "Reverse identify" means _____________________.

(5)  An MIT scientist stated that "we don't know what exactly _____________________.

(6)

Friday, January 18, 2013

Only Limited Information Needed For Pinpoint Identification of People From Online Genetic Information

Web Hunt For DNA Sequences Leaves Privacy Compromised by Gina Kolata.  The New York Times.  January 17, 2013.

Using only the long string of DNA letters, age of research subject, and state of the subject, researchers have successfully identified those subjects and their families.  The ease with which this information was unearthed poses questions for privacy policy in science and has implications for the open sharing data to further genetic research.  The guarantee of privacy granted to research subjects is called into question.  Story also covered here.

Thursday, November 1, 2012

DNA Variation And Disease: One Step to Understanding the Link

Scientists Expand Catalog of Human Genetic Variation by Eryn Brown.  Los Angeles Times.  October 31, 2012.

By sequencing the DNA of 1092 people from 14 populations, scientist of the 1000 Genomes Project have identified over 38 million DNA variants.  These variants could be key to understanding the genetic correlates of disease.  In the future the variants could provide a first level check to determine a possible genetic cause to the disease.

Another account at

Personalized Medicine Moves Closer by Robert Lee Hotz.  The Wall Street Journal.  October 31, 2012