Most -Used Diabetes Drug Works In a Different Way Than Previously Thought. Science Daily. January 6, 2012.
One of the classes of drugs used to control overactive glucose production in diabetes, biguanides, has been in use for over 50 years. The most popular drug in the class is metformin. However, the mechanism by which metformin decreases of production of glucose by the liver has not been completely understood until a research article in Nature which is reported on here. By more completely understanding the drug action of metformin, the authors of the study surmise that new drugs could be developed that focus on different cellular targets and therefore avoid some of the side effects of metformin.
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